Key Features:

• Zeno Trap Technology: Unique ion trap between quadrupole and TOF analyzer boosts sensitivity up to 20× by pulsing ions into the TOF analyzer with higher efficiency.

• High-Resolution Accurate Mass (HRAM): Achieves >40,000 FWHM resolution with <1 ppm mass accuracy for highly confident analyte identification.

• Ultra-Fast Acquisition: >133 spectra/sec, optimized for high-throughput UHPLC and DIA workflows.

• SWATH DIA Evolution: Next-generation data-independent acquisition with Zeno trap integration improves sensitivity for low-abundance ions.

• Expanded Dynamic Range: >5 orders of magnitude, enabling detection of trace biomarkers alongside abundant species.

• Enhanced Proteomic Coverage: Detects thousands of proteins in complex samples with superior depth compared to previous SCIEX QTOFs.

• Versatile Ion Sources: Compatible with Turbo V™ and DuoSpray® ion sources for ESI and APCI workflows.

• Advanced Polarity Switching: <20 ms for rapid dual-mode analysis.

• Improved Optics & Detection System: Enhanced ion transmission, reduced noise, and stable long-term performance.

• Software Ecosystem: SCIEX OS with integrated DIA-NN and Proteome Discoverer compatibility for proteomics, and compliance-ready for regulated industries.

• Regulatory Ready: Full support for GLP/GMP workflows with 21 CFR Part 11 compliance.

Applications:

• Proteomics: Deep proteome coverage, biomarker discovery, SWATH DIA-based large-cohort quantitative proteomics.

• Metabolomics & Lipidomics: Untargeted and targeted studies with higher sensitivity for low-abundance metabolites.

• Pharmaceutical Research: DMPK, pharmacokinetics, metabolite identification, impurity profiling, and lead optimization.

• Clinical & Translational Research: Large-scale biomarker verification, pathway elucidation, and translational medicine.

• Food & Environmental Testing: Ultra-trace analysis of contaminants, pesticides, pollutants, and toxins.

Specifications (Table):