Key Features:

• High-sensitivity triple quadrupole system designed for robust, reproducible quantitative LC-MS/MS analysis.

• Incorporates Shimadzu’s UFsweeper™ collision cell for ultra-fast and efficient collision-induced dissociation, reducing ion losses and enabling rapid MRM transitions.

• Polarity switching time of just 15 msec, enabling simultaneous analysis of positive and negative ions in a single run.

• Ultra-fast MRM transitions (up to 555 transitions/sec) for complex multi-analyte quantification.

• Improved ion optics and heated ESI/APCI sources for high sensitivity across a broad range of compounds.

• Wide dynamic range (over 5 orders of magnitude) for accurate quantification from trace-level to high-abundance compounds.

• Stability and robustness for continuous operation in high-throughput labs.

• Seamlessly integrated with Shimadzu LC platforms (Nexera or Prominence series) and LabSolutions software for full workflow automation.

• Compact footprint with energy-efficient vacuum system for routine and research labs.

• Full compliance with GLP/GMP and 21 CFR Part 11 regulations.

Applications:

• Pharmaceutical & Biopharma: Pharmacokinetics (PK), drug metabolism and pharmacokinetics (DMPK), bioanalysis, clinical trials.

• Food Safety: Pesticides, mycotoxins, veterinary drug residues, additives, contaminants.

• Environmental: Monitoring of water, soil, and air contaminants, trace organic pollutants.

• Forensics & Toxicology: Drug screening, doping control, forensic casework.

• Clinical Research: Biomarker quantitation, therapeutic drug monitoring (TDM).

• Industrial & Specialty Chemicals: QA/QC of raw materials, formulations, and specialty compounds.

• Academic Research: High-throughput targeted quantitation in complex biological and chemical samples.

Specifications: