Key Features:

• Integrated high-speed UHPLC-MS/MS platform combining the Shimadzu LCMS-8040 triple quadrupole with the Nexera X2 UHPLC system for unmatched throughput and sensitivity.

• Nexera X2 UHPLC technology delivers ultra-fast gradient switching, superior solvent delivery precision, and sub-2 µm particle compatibility for sharp chromatographic peaks.

• UFsweeper™ collision cell technology for rapid CID fragmentation with minimized ion losses, ensuring maximum sensitivity.

• Ultra-fast polarity switching (15 msec) enables simultaneous detection of positive and negative ions in a single run.

• High MRM transition rate (555 transitions/sec) for complex multi-analyte quantification in biological and environmental matrices.

• Wide linear dynamic range (≥ 5 orders of magnitude) supports trace detection and high-concentration quantification in the same analysis.

• Autosampler with overlapping injection capability, reducing cycle times and maximizing lab throughput.

• LabSolutions software integration for seamless control of both UHPLC and LC-MS, including data processing, quantitation, reporting, and regulatory compliance.

• Optimized for GLP/GMP-compliant labs, supporting 21 CFR Part 11 electronic record/e-signature requirements.

• Compact, energy-efficient, and designed for long-term robustness in routine and research-intensive environments.

Applications:

• Pharmaceutical & Biopharma: PK/PD studies, DMPK analysis, bioequivalence studies, metabolite ID, drug impurity profiling.

• Food Safety & Agriculture: Multi-residue pesticide screening, veterinary drug residue quantification, additive and contaminant testing.

• Environmental Analysis: Trace-level quantification of pollutants, PPCPs (pharmaceuticals and personal care products), pesticides, and herbicides in water/soil.

• Forensics & Toxicology: Drug screening, forensic toxicology, doping control, forensic casework analysis.

• Clinical Research: Biomarker quantitation, therapeutic drug monitoring (TDM), proteomics-related targeted analysis.

• Industrial & Specialty Chemicals: QA/QC of formulations, polymer analysis, chemical process monitoring.

• Academic Research: High-throughput targeted metabolomics and advanced quantitative workflows.

Specifications: