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Shimadzu LCMS-8045 Triple Quadrupole LC/MS with Nexera X2 UHPLC high-performance, integrated UHPLC-MS/MS system for pharmaceutical, food safety, environmental, forensic, and clinical applications.
  • Shimadzu LCMS-8045 Triple Quadrupole LC/MS with Nexera X2 UHPLC high-performance, integrated UHPLC-MS/MS system for pharmaceutical, food safety, environmental, forensic, and clinical applications.
  • Shimadzu LCMS-8045 Triple Quadrupole LC/MS with Nexera X2 UHPLC high-performance, integrated UHPLC-MS/MS system for pharmaceutical, food safety, environmental, forensic, and clinical applications.
Shimadzu LCMS-8045 Triple Quadrupole LC/MS with Nexera X2 UHPLC High-Performance LC-MS/MS System
$0.00

  • Key Features:

    • Integrated UHPLC-MS/MS platform combining the Shimadzu LCMS-8045 triple quadrupole system with the Nexera X2 UHPLC, providing high-performance separation and quantitation.

    • Nexera X2 UHPLC offers sub-2 µm particle compatibility, ultra-fast gradient switching, and superior solvent delivery precision for excellent chromatographic resolution.

    • UFsweeper™ collision cell technology ensures efficient CID fragmentation with minimal ion loss, enhancing sensitivity in quantitative workflows.

    • Polarity switching of 30 msec allows fast switching between positive and negative ion detection, enabling comprehensive profiling in a single run.

    • Up to 500 MRM transitions/sec for simultaneous detection of large numbers of analytes, making it suitable for complex food, clinical, and environmental samples.

    • Dynamic range of ≥ 5 orders of magnitude, supporting accurate quantitation from trace to high-abundance analytes.

    • Nexera X2 autosampler with overlapping injection reduces cycle times, boosting overall throughput.

    • LabSolutions software offers seamless LC-MS integration, compliance features, quantitation tools, and customizable reporting.

    • Optimized for routine, regulatory, and research laboratories, with simplified maintenance and extended operational stability.

    • Full support for GLP/GMP and 21 CFR Part 11 compliance, ensuring secure electronic records and data integrity.

  • Applications:

    • Pharmaceutical & Biopharma: DMPK studies, drug discovery support, bioequivalence testing, impurity profiling, metabolite quantitation.

    • Food Safety & Agriculture: Multi-residue pesticide screening, mycotoxin monitoring, veterinary drug residues, additive and contaminant testing.

    • Environmental Analysis: Monitoring pollutants, PPCPs, pesticides, herbicides, and trace organic contaminants in water, soil, and air.

    • Forensic & Toxicology: Drug screening, forensic toxicology, doping control, and casework applications.

    • Clinical Research: Biomarker quantification, therapeutic drug monitoring (TDM), targeted metabolomics.

    • Industrial & Specialty Chemicals: QA/QC for formulations, manufacturing process monitoring, raw material analysis.

    • Academic & Government Labs: High-throughput targeted quantitation studies across multiple disciplines.

  • Specifications:

Parameter Specification
System Type Integrated UHPLC-Triple Quadrupole LC-MS/MS System
UHPLC Platform Shimadzu Nexera X2 UHPLC
LC Features High-pressure operation, sub-2 µm particle compatibility, ultra-fast gradient switching
Autosampler Nexera X2 with overlapping injection capability, high sample throughput
Ionization Sources ESI (Electrospray Ionization), APCI (Atmospheric Pressure Chemical Ionization)
Mass Range m/z 2–2,000 (application dependent)
Scan Modes MRM, SIM, Product Ion Scan, Precursor Ion Scan, Neutral Loss Scan
Scan Speed Up to 30,000 u/sec
Polarity Switching 30 msec
MRM Capability Up to 500 transitions/sec
Collision Cell UFsweeper™ technology for efficient CID with minimized ion loss
Dynamic Range ≥ 5 orders of magnitude
Sensitivity High femtogram-level detection capability
Vacuum System High-capacity turbomolecular pumps
Software LabSolutions LCMS – integrated LC-MS control, quantitation, compliance tools
Compliance GLP/GMP, 21 CFR Part 11


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