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Key Features:
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Balanced performance system designed for routine quantitative LC-MS/MS workflows across pharmaceuticals, food safety, clinical, and environmental applications.
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Incorporates Shimadzu’s UFsweeper™ collision cell technology, enabling fast collision-induced dissociation with minimized ion losses.
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Polarity switching of 30 msec, supporting rapid detection of both positive and negative ions.
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Fast MRM acquisition capability (up to 500 transitions/sec) for simultaneous analysis of multiple analytes.
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High sensitivity and selectivity with robust ion optics and heated ESI/APCI ion sources.
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Dynamic range ≥ 5 orders of magnitude, allowing trace detection to high-abundance compound quantitation in the same run.
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Designed for reliability and stability, with simplified maintenance and extended uptime for routine laboratories.
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Fully compatible with Shimadzu Nexera UHPLC/Prominence LC platforms for enhanced chromatographic performance.
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Seamlessly integrated with LabSolutions software, providing full control, data analysis, reporting, and compliance management.
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Supports GLP/GMP and 21 CFR Part 11 electronic record requirements.
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Applications:
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Pharmaceutical & Biopharma: Drug discovery, DMPK, bioequivalence studies, impurity profiling, metabolite monitoring.
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Food Safety & Agriculture: Quantitative detection of pesticide residues, mycotoxins, additives, veterinary drug residues.
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Environmental Monitoring: Analysis of water, soil, and air contaminants, PPCPs (pharmaceuticals and personal care products).
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Forensics & Toxicology: Drug screening, toxicological analysis, forensic casework, doping control.
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Clinical Research & Diagnostics: Therapeutic drug monitoring (TDM), biomarker quantitation, targeted metabolomics.
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Industrial & Specialty Chemicals: Quality assurance and quality control (QA/QC) of formulations and raw materials.
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Academic & Government Labs: Advanced targeted quantitation in multi-disciplinary research settings.
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Specifications:
Parameter | Specification |
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System Type | Triple Quadrupole LC-MS/MS |
Ionization Sources | ESI (Electrospray Ionization), APCI (Atmospheric Pressure Chemical Ionization) |
Mass Range | m/z 2–2,000 (application dependent) |
Scan Modes | MRM, SIM, Product Ion Scan, Precursor Ion Scan, Neutral Loss Scan |
Scan Speed | Up to 30,000 u/sec |
Polarity Switching | 30 msec |
MRM Capability | Up to 500 transitions/sec |
Collision Cell | UFsweeper™ technology for efficient CID and minimal ion loss |
Dynamic Range | ≥ 5 orders of magnitude |
Sensitivity | High femtogram-level sensitivity |
Vacuum System | High-capacity turbomolecular pumps |
LC Compatibility | Nexera UHPLC, Prominence LC platforms |
Software | LabSolutions LCMS – integrated LC-MS control, data handling, compliance tools |
Compliance | GLP/GMP, 21 CFR Part 11 |