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Key Features:
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Ultra-high sensitivity triple quadrupole LC-MS/MS system designed for advanced quantitative workflows requiring femtogram-level detection.
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Equipped with UFsweeper™ III collision cell technology, enabling high-efficiency CID with virtually no ion loss.
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Polarity switching speed of 5 msec – among the fastest available – enabling near-simultaneous detection of positive and negative ions in one run.
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Ultra-fast MRM capability (up to 555 transitions/sec) for high-throughput multi-analyte quantitation.
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Scan speed of 30,000 u/sec for rapid and accurate data acquisition.
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Robust ion source options (ESI, APCI, DUIS) optimized for high sensitivity and broad application coverage.
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Wide linear dynamic range of ≥ 6 orders of magnitude, supporting both trace-level detection and high-concentration quantitation.
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Compatible with Shimadzu Nexera UHPLC series, ensuring high chromatographic resolution with sub-2 µm particle performance.
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Full integration with LabSolutions LCMS software for advanced data processing, automation, compliance, and customizable reporting.
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Built for ruggedness and 24/7 operation, reducing downtime in high-throughput research and regulated labs.
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Compliant with GLP/GMP and 21 CFR Part 11 standards.
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Applications:
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Pharmaceutical & Biopharma: PK/PD studies, DMPK workflows, metabolite ID, bioequivalence testing, trace impurity profiling.
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Food Safety & Agriculture: Multi-residue pesticide screening, mycotoxin detection, veterinary drug residues, food additive and contaminant analysis.
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Environmental Testing: Trace organic pollutants, endocrine disruptors, PPCPs, herbicides, pesticides, water/soil contamination studies.
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Forensics & Toxicology: Drug screening, doping control, forensic toxicology investigations, controlled substance quantification.
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Clinical Research: Targeted metabolomics, biomarker validation, therapeutic drug monitoring (TDM).
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Industrial Chemicals: Quality control of fine chemicals, polymers, and specialty formulations.
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Academic & Core Labs: Advanced multi-analyte quantitation for collaborative and interdisciplinary research.
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Specifications:
Parameter | Specification |
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System Type | Triple Quadrupole LC-MS/MS |
Ionization Sources | ESI, APCI, DUIS (Dual Ion Source) |
Mass Range | m/z 2–2,000 (expandable with options) |
Scan Modes | MRM, SIM, Product Ion, Precursor Ion, Neutral Loss |
Scan Speed | Up to 30,000 u/sec |
Polarity Switching | 5 msec (ultra-fast) |
MRM Capability | Up to 555 transitions/sec |
Collision Cell | UFsweeper™ III collision cell, high-efficiency CID with minimal ion loss |
Dynamic Range | ≥ 6 orders of magnitude |
Sensitivity | Femtogram-level detection |
Vacuum System | High-performance turbomolecular pump system |
LC Compatibility | Nexera UHPLC, Prominence UFLC |
Software | LabSolutions LCMS – integrated LC/MS control, compliance, automation |
Compliance | GLP/GMP, 21 CFR Part 11 |