Key Features:

• Fully integrated UHPLC-MS/MS platform combining the Shimadzu LCMS-8050 triple quadrupole mass spectrometer with the Nexera X2 UHPLC system, engineered for ultra-fast, high-sensitivity quantitative workflows.

• Nexera X2 UHPLC system provides sub-2 µm particle compatibility, high-pressure operation, precise solvent delivery, and rapid gradient switching, ensuring optimal peak resolution and minimal carryover.

• UFsweeper™ III collision cell technology enables ultra-efficient CID with near-zero ion loss, ensuring highly accurate quantitation.

• Polarity switching in just 5 msec, one of the fastest in the industry, enabling near-simultaneous detection of positive and negative ions.

• Ultra-fast MRM acquisition (up to 555 transitions/sec) for high-throughput analysis of complex matrices.

• Scan speed of 30,000 u/sec, ensuring fast and precise data capture without loss of resolution.

• Dynamic range of ≥ 6 orders of magnitude, providing reliable quantitation across trace-level to high-abundance analytes.

• Nexera X2 autosampler with overlapping injection for ultra-fast sample turnaround and maximum throughput.

• LabSolutions LCMS software provides unified LC-MS control, quantitation workflows, advanced automation, secure data handling, and full regulatory compliance support.

• Built for continuous operation in demanding labs, with robust performance, minimized maintenance, and long-term system stability.

• Supports GLP/GMP and 21 CFR Part 11 compliance, ensuring data integrity and traceability for regulated industries.

Applications:

• Pharmaceutical & Biopharma: PK/PD and DMPK studies, drug metabolism, bioequivalence testing, impurity analysis, metabolite identification, biotherapeutics quantitation.

• Food Safety & Agriculture: High-throughput pesticide screening, mycotoxin detection, veterinary drug residues, additives, and contaminants.

• Environmental Monitoring: Trace-level detection of endocrine disruptors, PPCPs, herbicides, pesticides, and pollutants in environmental samples.

• Forensics & Toxicology: Toxicology analysis, doping control, forensic drug screening, quantitation of controlled substances.

• Clinical Research: Biomarker validation, therapeutic drug monitoring (TDM), targeted metabolomics for clinical studies.

• Industrial & Specialty Chemicals: QA/QC of formulations, raw material testing, and specialty chemical analysis.

• Academic & Core Research Facilities: Advanced quantitative proteomics, metabolomics, and interdisciplinary research requiring high-sensitivity and high-throughput performance.

Specifications: