Pickup currently not available
Key Features:
-
Dedicated Gel Permeation Chromatography (GPC/SEC) configuration built on Shimadzu’s reliable Prominence HPLC platform.
-
High-precision solvent delivery system with low-pulsation pumps ensures reproducible molecular weight distribution data.
-
Accurate flow rate control across a broad range, critical for polymer molecular weight determination.
-
Multiple detector compatibility including refractive index (RI), UV-Vis, photodiode array (PDA), and light scattering (MALS) detectors for comprehensive polymer characterization.
-
Flexible autosampler design supports both routine high-throughput QC and complex R&D workflows.
-
Column oven with precise temperature control, enabling stable baselines and reproducibility across long polymer separations.
-
Wide solvent compatibility (THF, DMF, chloroform, aqueous SEC solvents), supporting both synthetic and biopolymer applications.
-
High system stability and reliability for extended unattended operation in QC labs.
-
Advanced LCsolution software integration provides automated data acquisition, calibration curve generation, molecular weight calculations, and data reporting.
-
21 CFR Part 11 compliance for regulated environments with secure audit trails and electronic records.
-
Low carryover design with optimized sample loop and injection port for sensitive polymer and biopolymer analysis.
-
Expandable modular architecture, allowing integration with Shimadzu’s RID-20A refractive index detector or advanced multi-detector systems for comprehensive macromolecular analysis.
Applications:
-
Polymer Science & Industry: Determination of polymer molecular weight distribution, polydispersity, and structural branching in synthetic polymers.
-
Pharmaceutical & Biopharmaceutical Research: SEC analysis of therapeutic proteins, antibody aggregates, and other biomacromolecules.
-
Quality Control: Routine polymer QC in plastics, coatings, elastomers, adhesives, and specialty chemicals industries.
-
Academic & Research Laboratories: Advanced characterization of new polymer formulations and biomaterials.
-
Food & Environmental Science: Characterization of polysaccharides, natural polymers, and macromolecular additives.
-
Material Development: Investigation of advanced polymers for packaging, electronics, and medical applications.
Specifications:
| Parameter | Specification |
|---|---|
| Chromatography Platform | Shimadzu Prominence HPLC configured for GPC/SEC |
| Separation Principle | Gel Permeation Chromatography / Size Exclusion Chromatography |
| Pump | Isocratic high-precision solvent delivery with low pulsation |
| Flow Rate Range | 0.001 – 10.0 mL/min (high accuracy and reproducibility) |
| Detectors (options) | Refractive Index (RID-20A), UV, PDA, MALS, viscometer |
| Autosampler | SIL series autosampler, high-precision, variable injection volume |
| Injection Volume Range | 0.1 – 100 µL (programmable) |
| Sample Capacity | Vials and microplates (varies by configuration) |
| Column Oven | Temperature-controlled, ambient +10 °C to 85 °C |
| Solvent Compatibility | THF, DMF, chloroform, aqueous SEC solvents |
| Acquisition Modes | Isocratic (typical for SEC/GPC), multi-detector integration |
| Software | LCsolution CDS with GPC option for molecular weight calibration |
| Data Processing | Molecular weight averages (Mn, Mw, Mz), PDI, calibration with standards |
| Compliance | GLP/GMP, 21 CFR Part 11 ready |
| Expandability | Modular – supports additional detectors, fraction collector |
| System Reliability | Designed for high-stability long-duration analysis |