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Key Features:
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The Shimadzu Prominence HPLC System is a modular high-performance liquid chromatography platform, widely used for analytical and quality control laboratories.
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Equipped with the RF-20A Fluorescence Detector, offering ultra-high sensitivity and selectivity for compounds that naturally fluoresce or are derivatized with fluorescent tags.
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Detects analytes at concentrations down to sub-picogram levels, making it ideal for trace analysis.
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Wavelength range of 200–650 nm (excitation) and 250–750 nm (emission) with high signal-to-noise ratio and rapid response.
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Capable of 3D fluorescence scanning, allowing determination of excitation/emission spectra and optimization of analytical conditions.
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Modular design allows integration with pumps, autosamplers, column ovens, and additional detectors (UV, PDA, RID) in the Prominence series.
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Controlled by Shimadzu LabSolutions software, with full regulatory compliance support for GLP/GMP and 21 CFR Part 11 environments.
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Applications:
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Pharmaceutical & Biopharmaceuticals: Quantification of drugs and metabolites, impurity profiling, pharmacokinetic studies.
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Biochemistry & Life Sciences: Amino acid analysis, protein and peptide detection, nucleic acid derivatives, enzyme assays.
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Environmental Analysis: Trace detection of PAHs (polycyclic aromatic hydrocarbons), pesticides, and contaminants in water and soil.
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Food & Nutraceuticals: Vitamin assays, natural product analysis, detection of aflatoxins, food additives, and fluorescent compounds.
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Clinical Research: Hormone analysis, biomarker studies, clinical pharmacology.
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Forensic & Toxicology: Screening of fluorescent drug metabolites and toxins.
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Specifications:
Parameter | Specification |
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System Type | Modular HPLC system with fluorescence detection |
Detector Model | RF-20A Fluorescence Detector |
Excitation Wavelength Range | 200–650 nm |
Emission Wavelength Range | 250–750 nm |
Sensitivity | Sub-picogram-level detection |
Features | 3D fluorescence scanning, programmable wavelength switching, high S/N ratio |
Pump Options | Isocratic, binary, or quaternary solvent delivery (flow range 0.001–10 mL/min) |
Autosampler | High-precision injection, low carryover, variable volume |
Column Oven | Temperature range: ambient +4 °C to 85 °C |
Software | Shimadzu LabSolutions CDS |
Compliance | GLP/GMP, 21 CFR Part 11 compliant |