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Thermo Scientific Dionex ICS-2100 Ion Chromatography System with AS-AP Autosampler  Automated RFIC system for high-throughput anion and cation analysis in environmental, pharmaceutical, food, and industrial labs

Key Features:

  • Reagent-Free Ion Chromatography with Eluent Generation (RFIC-EG): Eliminates the need for manual eluent preparation, ensuring reproducible and contamination-free analyses.

  • All-in-one IC design: Integrated pump, suppressor, eluent generation, and conductivity detection in a single, compact unit.

  • High-sensitivity conductivity detector with temperature compensation, enabling trace-level detection of ionic species.

  • AS-AP autosampler integration:

    • High-capacity sample handling (vials, well plates, or combination racks).

    • Precise and reproducible injections with variable injection volumes.

    • Unattended continuous operation for high-throughput laboratories.

    • Advanced features such as inline filtration, intelligent sample scheduling, and priority re-injections.

  • Dynamic range and linearity allow simultaneous determination of major ions and trace contaminants in the same run.

  • Electrolytic suppression technology for stable baselines and enhanced signal-to-noise ratios.

  • Supports a broad range of applications with columns for inorganic anions, cations, organic acids, amines, and polar compounds.

  • Chromeleon CDS software for complete data integration, automated peak identification, calibration, quantitation, reporting, and secure compliance.

  • 21 CFR Part 11 ready, supporting GMP/GLP laboratories with full audit trail and electronic record-keeping.

  • Expandable modular design: Add-on detectors (UV/Vis, amperometric) for specialized analyses.

  • Designed for both regulated QC environments and research workflows, offering robustness with automation.


Applications:

  • Environmental Testing: Automated monitoring of anions and cations in drinking water, wastewater, ground and surface water, ensuring compliance with EPA, ISO, and other standards.

  • Pharmaceutical & Biopharmaceutical: Routine counter-ion analysis, excipient monitoring, and raw material QC.

  • Food & Beverage Industry: Analysis of organic acids, ionic preservatives, and nutritional ions.

  • Industrial QC: Semiconductor water purity testing, chemical production monitoring, and boiler water analysis in power plants.

  • Agriculture: Fertilizer composition testing and soil ion profile analysis.

  • Academic & Research Labs: Automated ionic compound analysis for teaching, research, and advanced method development.


Specifications:

Parameter Specification
Chromatography Platform Thermo Scientific Dionex ICS-2100 with AS-AP Autosampler
Separation Principle Reagent-Free Ion Chromatography with Electrolytic Eluent Generation (RFIC-EG)
Pump Type Isocratic with electrolytic eluent generation
Flow Rate Range 0.1 – 2.0 mL/min
Suppression Technology Dionex electrolytic suppressors for anion and cation separations
Detector (standard) Conductivity detector with temperature compensation
Additional Detectors (optional) UV/Vis detector, amperometric detector
Autosampler AS-AP (high-throughput, low-carryover, priority sample capability)
Sample Capacity Configurable racks for 5 mL vials (up to 768 samples) or microplates
Injection Volume Range 0.1 – 100 µL (programmable, precision injections)
Special Autosampler Features Inline filtration, vial-based or plate-based flexibility, intelligent scheduling
Column Oven Optional, temperature-controlled chamber
Eluent Compatibility Carbonate, hydroxide, methanesulfonic acid generated by eluent generator
Acquisition Modes Isocratic separations (with gradient eluent generation capability)
Software Chromeleon CDS with secure compliance and automation tools
Data Processing Automated quantitation, calibration curves, multi-point standards
Compliance GLP/GMP, 21 CFR Part 11 ready
Expandability Modular, supports multi-detector configurations and advanced IC accessories
System Reliability Robust for unattended, high-throughput operation in QC and research labs


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