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Key Features:
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Flagship high-performance ion chromatography system designed for maximum versatility, sensitivity, and throughput.
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Dual system configuration possible: run two analyses (e.g., anion and cation) simultaneously on one instrument.
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Reagent-Free Ion Chromatography with Eluent Generation (RFIC-EG): Automated eluent preparation eliminates manual mixing, ensuring reproducibility and reducing contamination.
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High-pressure IC (HPIC) capability, enabling faster separations with smaller particle size columns for higher efficiency.
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Electrolytic suppressors (anion and cation) with extended lifetimes for consistent low-noise baselines.
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Broad detector options: Conductivity (standard), UV/Vis, amperometric, electrochemical, mass spectrometry coupling (IC-MS), charged aerosol detection (CAD).
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Flexible autosampler compatibility (AS-AP, AS-DV, AS-HV) supporting high-capacity sample runs with intelligent scheduling.
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Extended application range from trace-level detection to high-concentration analysis in the same run.
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Integrated temperature-controlled compartments for columns and detectors, enhancing reproducibility.
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Chromeleon Chromatography Data System (CDS) with advanced compliance, quantitation, and reporting features.
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21 CFR Part 11 ready with full data integrity and audit trail management for regulated labs.
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Modular and expandable platform – users can configure and scale the system to specific application needs.
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Compatibility with high-capacity IonPac columns for environmental, food, pharmaceutical, and industrial workflows.
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MS coupling support – IC-MS for enhanced selectivity and sensitivity for complex matrices.
Applications:
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Environmental Testing: Analysis of major anions (fluoride, chloride, nitrate, sulfate, phosphate) and cations (sodium, potassium, calcium, magnesium, ammonium) in drinking water, wastewater, and soil extracts.
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Trace Contaminant Monitoring: Bromate, perchlorate, haloacetic acids, and oxyhalide monitoring in water.
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Pharmaceutical & Biopharmaceuticals: Counter-ion analysis, excipient QC, process monitoring, and cleaning validation.
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Food & Beverage: Organic acid profiling, additive monitoring, ionic preservative analysis, and nutritional ion quantification.
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Power & Energy Industry: Boiler water chemistry, power plant cycle chemistry monitoring, and corrosion ion detection.
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Semiconductor Industry: Ultrapure water analysis for ionic contamination control.
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Academic & Research Institutions: Advanced ionic compound analysis, method development, and ionic speciation studies.
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Coupled IC-MS Workflows: Trace ion analysis in complex matrices where selectivity and sensitivity are critical.
Specifications:
Parameter | Specification |
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Chromatography Platform | Thermo Scientific Dionex ICS-5000+ HPIC |
Separation Principle | High-Performance Reagent-Free Ion Chromatography (RFIC-EG) |
Pump Type | Isocratic, gradient, and RFIC eluent generation |
Flow Rate Range | 0.001 – 5.0 mL/min |
Pressure Capability | Up to 5000 psi (HPIC – high backpressure capable) |
Suppression Technology | Dionex electrolytic suppressors (anion and cation) |
Detectors (standard) | Conductivity with temperature compensation |
Additional Detectors (optional) | UV/Vis, amperometric, electrochemical, CAD, MS coupling |
Autosamplers | AS-AP, AS-DV, AS-HV (high-volume and high-capacity options) |
Injection Volume Range | 0.1 – 100 µL (programmable) |
Sample Capacity | Up to 768 samples with AS-AP (microplate format) |
Column Oven | Temperature-controlled (ambient +10 °C to 85 °C) |
Eluent Compatibility | Carbonate, hydroxide, methanesulfonic acid, and RFIC-generated eluents |
Acquisition Modes | Isocratic, gradient, dual system capability |
Software | Chromeleon Chromatography Data System |
Data Processing | Quantitation, calibration, peak identification, trace-level reporting |
Compliance | GLP/GMP, 21 CFR Part 11 ready |
Expandability | Dual system capability, MS coupling, additional detectors |
System Reliability | Designed for high-throughput, trace-level sensitivity, and multi-application use |