Skip to product information
Thermo Scientific Dionex ICS-5000+ Ion Chromatography System High-performance RFIC and HPIC system for advanced anion, cation, and ionic compound analysis in environmental, pharmaceutical, food, and industrial applications

Key Features:

  • Flagship high-performance ion chromatography system designed for maximum versatility, sensitivity, and throughput.

  • Dual system configuration possible: run two analyses (e.g., anion and cation) simultaneously on one instrument.

  • Reagent-Free Ion Chromatography with Eluent Generation (RFIC-EG): Automated eluent preparation eliminates manual mixing, ensuring reproducibility and reducing contamination.

  • High-pressure IC (HPIC) capability, enabling faster separations with smaller particle size columns for higher efficiency.

  • Electrolytic suppressors (anion and cation) with extended lifetimes for consistent low-noise baselines.

  • Broad detector options: Conductivity (standard), UV/Vis, amperometric, electrochemical, mass spectrometry coupling (IC-MS), charged aerosol detection (CAD).

  • Flexible autosampler compatibility (AS-AP, AS-DV, AS-HV) supporting high-capacity sample runs with intelligent scheduling.

  • Extended application range from trace-level detection to high-concentration analysis in the same run.

  • Integrated temperature-controlled compartments for columns and detectors, enhancing reproducibility.

  • Chromeleon Chromatography Data System (CDS) with advanced compliance, quantitation, and reporting features.

  • 21 CFR Part 11 ready with full data integrity and audit trail management for regulated labs.

  • Modular and expandable platform – users can configure and scale the system to specific application needs.

  • Compatibility with high-capacity IonPac columns for environmental, food, pharmaceutical, and industrial workflows.

  • MS coupling support – IC-MS for enhanced selectivity and sensitivity for complex matrices.


Applications:

  • Environmental Testing: Analysis of major anions (fluoride, chloride, nitrate, sulfate, phosphate) and cations (sodium, potassium, calcium, magnesium, ammonium) in drinking water, wastewater, and soil extracts.

  • Trace Contaminant Monitoring: Bromate, perchlorate, haloacetic acids, and oxyhalide monitoring in water.

  • Pharmaceutical & Biopharmaceuticals: Counter-ion analysis, excipient QC, process monitoring, and cleaning validation.

  • Food & Beverage: Organic acid profiling, additive monitoring, ionic preservative analysis, and nutritional ion quantification.

  • Power & Energy Industry: Boiler water chemistry, power plant cycle chemistry monitoring, and corrosion ion detection.

  • Semiconductor Industry: Ultrapure water analysis for ionic contamination control.

  • Academic & Research Institutions: Advanced ionic compound analysis, method development, and ionic speciation studies.

  • Coupled IC-MS Workflows: Trace ion analysis in complex matrices where selectivity and sensitivity are critical.


Specifications:

Parameter Specification
Chromatography Platform Thermo Scientific Dionex ICS-5000+ HPIC
Separation Principle High-Performance Reagent-Free Ion Chromatography (RFIC-EG)
Pump Type Isocratic, gradient, and RFIC eluent generation
Flow Rate Range 0.001 – 5.0 mL/min
Pressure Capability Up to 5000 psi (HPIC – high backpressure capable)
Suppression Technology Dionex electrolytic suppressors (anion and cation)
Detectors (standard) Conductivity with temperature compensation
Additional Detectors (optional) UV/Vis, amperometric, electrochemical, CAD, MS coupling
Autosamplers AS-AP, AS-DV, AS-HV (high-volume and high-capacity options)
Injection Volume Range 0.1 – 100 µL (programmable)
Sample Capacity Up to 768 samples with AS-AP (microplate format)
Column Oven Temperature-controlled (ambient +10 °C to 85 °C)
Eluent Compatibility Carbonate, hydroxide, methanesulfonic acid, and RFIC-generated eluents
Acquisition Modes Isocratic, gradient, dual system capability
Software Chromeleon Chromatography Data System
Data Processing Quantitation, calibration, peak identification, trace-level reporting
Compliance GLP/GMP, 21 CFR Part 11 ready
Expandability Dual system capability, MS coupling, additional detectors
System Reliability Designed for high-throughput, trace-level sensitivity, and multi-application use


You may also like