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Key Features:
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Advanced HPIC system combining the Dionex Integrion platform with the high-capacity Dionex AS-AP autosampler for fully automated workflows.
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Reagent-Free IC (RFIC-EG): Automated eluent generation from deionized water reduces manual preparation and improves reproducibility.
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High-pressure operation (HPIC) supports modern sub-3 µm particle columns, enabling faster separations with higher resolution.
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AS-AP autosampler integration: Flexible configurations for standard vials, deep-well plates, or microplates, supporting up to 768 samples.
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Multiple injection modes: Full-loop, partial-loop, and push-loop for maximum flexibility across concentration ranges.
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Automated workflows: Sample preparation options such as dilution, internal standard addition, and sample preconcentration enhance productivity.
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Column oven with temperature control ensures precise, reproducible separations.
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Touchscreen user interface with system diagnostics, run setup, and real-time monitoring.
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Consumables management system (RFID/barcoded columns and suppressors) for traceability and error prevention.
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Detector flexibility: Standard conductivity detection with optional UV/Vis, electrochemical, and MS coupling for extended workflows.
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Chromeleon Chromatography Data System for full instrument control, compliance, and advanced reporting.
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21 CFR Part 11 compliance ready, ensuring regulatory suitability for pharmaceutical and GMP labs.
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Scalable modular design allows future upgrades in detectors, sample capacity, or IC-MS coupling.
Applications:
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Environmental Testing: Routine and trace-level monitoring of anions (fluoride, chloride, nitrate, nitrite, sulfate, phosphate) and cations in water and wastewater, including disinfection byproducts and oxyhalides.
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Pharmaceutical and Biopharma QC: Counter-ion analysis, excipient verification, cleaning validation, and monitoring ionic species in biologics and formulations.
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Food & Beverage Industry: Analysis of organic acids, preservatives, sweeteners, additives, and mineral content.
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Energy and Power Plants: Ionic contamination control in boiler feedwater, steam cycle monitoring, and cooling systems.
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Semiconductor Industry: Ultrapure water ionic impurity testing for contamination control in electronic-grade manufacturing.
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Industrial & Chemical Manufacturing: Quality control of raw materials, ionic additives, and process monitoring.
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Academic & Research: Advanced ionic species profiling, ionic speciation studies, and method development with IC-MS.
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High-Throughput Labs: Environmental monitoring agencies, contract labs, and QC departments requiring automated sample processing with minimal human intervention.
Specifications:
Parameter | Specification |
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Chromatography Platform | Thermo Scientific Dionex Integrion HPIC |
Separation Principle | High-Performance Reagent-Free Ion Chromatography (RFIC-EG) |
Pump Type | Dual piston, RFIC-compatible |
Flow Rate Range | 0.001 – 5.0 mL/min |
Pressure Capability | Up to 5000 psi (supports HPIC small-particle columns) |
Suppression Technology | Dionex electrolytic suppressors (anion and cation) |
Detectors (standard) | Conductivity with temperature compensation |
Optional Detectors | UV/Vis, amperometric, electrochemical, MS coupling |
Autosampler | Dionex AS-AP with full integration |
Sample Capacity | Up to 768 samples (microplates, vials, deep-well plates) |
Injection Volume Range | 0.1 – 100 µL (programmable, full-loop, partial-loop, push-loop) |
Autosampler Functions | Sample dilution, internal standard addition, preconcentration workflows |
Column Oven | Programmable, ambient +10 °C to 85 °C |
Eluent Compatibility | Hydroxide, carbonate, methanesulfonic acid, RFIC-generated eluents |
Acquisition Modes | Isocratic and gradient |
User Interface | Touchscreen with diagnostic and method setup tools |
Consumables Tracking | RFID/barcoded suppressors, columns, eluent cartridges |
Software | Thermo Scientific Chromeleon CDS |
Data Processing | Calibration, quantitation, trace analysis, advanced compliance reporting |
Compliance | GLP/GMP, 21 CFR Part 11 ready |
Maintenance | Automated priming, shutdown, and diagnostic alerts |
Expandability | Detector add-ons, MS coupling, modular upgrades |