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"Thermo Scientific Dionex Integrion HPIC System with AS-AP Autosampler – High-performance reagent-free ion chromatography system with automated sample handling for environmental, pharmaceutical, food, and industrial ionic analysis"

Key Features:

  • Advanced HPIC system combining the Dionex Integrion platform with the high-capacity Dionex AS-AP autosampler for fully automated workflows.

  • Reagent-Free IC (RFIC-EG): Automated eluent generation from deionized water reduces manual preparation and improves reproducibility.

  • High-pressure operation (HPIC) supports modern sub-3 µm particle columns, enabling faster separations with higher resolution.

  • AS-AP autosampler integration: Flexible configurations for standard vials, deep-well plates, or microplates, supporting up to 768 samples.

  • Multiple injection modes: Full-loop, partial-loop, and push-loop for maximum flexibility across concentration ranges.

  • Automated workflows: Sample preparation options such as dilution, internal standard addition, and sample preconcentration enhance productivity.

  • Column oven with temperature control ensures precise, reproducible separations.

  • Touchscreen user interface with system diagnostics, run setup, and real-time monitoring.

  • Consumables management system (RFID/barcoded columns and suppressors) for traceability and error prevention.

  • Detector flexibility: Standard conductivity detection with optional UV/Vis, electrochemical, and MS coupling for extended workflows.

  • Chromeleon Chromatography Data System for full instrument control, compliance, and advanced reporting.

  • 21 CFR Part 11 compliance ready, ensuring regulatory suitability for pharmaceutical and GMP labs.

  • Scalable modular design allows future upgrades in detectors, sample capacity, or IC-MS coupling.


Applications:

  • Environmental Testing: Routine and trace-level monitoring of anions (fluoride, chloride, nitrate, nitrite, sulfate, phosphate) and cations in water and wastewater, including disinfection byproducts and oxyhalides.

  • Pharmaceutical and Biopharma QC: Counter-ion analysis, excipient verification, cleaning validation, and monitoring ionic species in biologics and formulations.

  • Food & Beverage Industry: Analysis of organic acids, preservatives, sweeteners, additives, and mineral content.

  • Energy and Power Plants: Ionic contamination control in boiler feedwater, steam cycle monitoring, and cooling systems.

  • Semiconductor Industry: Ultrapure water ionic impurity testing for contamination control in electronic-grade manufacturing.

  • Industrial & Chemical Manufacturing: Quality control of raw materials, ionic additives, and process monitoring.

  • Academic & Research: Advanced ionic species profiling, ionic speciation studies, and method development with IC-MS.

  • High-Throughput Labs: Environmental monitoring agencies, contract labs, and QC departments requiring automated sample processing with minimal human intervention.


Specifications:

Parameter Specification
Chromatography Platform Thermo Scientific Dionex Integrion HPIC
Separation Principle High-Performance Reagent-Free Ion Chromatography (RFIC-EG)
Pump Type Dual piston, RFIC-compatible
Flow Rate Range 0.001 – 5.0 mL/min
Pressure Capability Up to 5000 psi (supports HPIC small-particle columns)
Suppression Technology Dionex electrolytic suppressors (anion and cation)
Detectors (standard) Conductivity with temperature compensation
Optional Detectors UV/Vis, amperometric, electrochemical, MS coupling
Autosampler Dionex AS-AP with full integration
Sample Capacity Up to 768 samples (microplates, vials, deep-well plates)
Injection Volume Range 0.1 – 100 µL (programmable, full-loop, partial-loop, push-loop)
Autosampler Functions Sample dilution, internal standard addition, preconcentration workflows
Column Oven Programmable, ambient +10 °C to 85 °C
Eluent Compatibility Hydroxide, carbonate, methanesulfonic acid, RFIC-generated eluents
Acquisition Modes Isocratic and gradient
User Interface Touchscreen with diagnostic and method setup tools
Consumables Tracking RFID/barcoded suppressors, columns, eluent cartridges
Software Thermo Scientific Chromeleon CDS
Data Processing Calibration, quantitation, trace analysis, advanced compliance reporting
Compliance GLP/GMP, 21 CFR Part 11 ready
Maintenance Automated priming, shutdown, and diagnostic alerts
Expandability Detector add-ons, MS coupling, modular upgrades


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