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Key Features:
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Triple Quadrupole LC-MS/MS system engineered for enhanced sensitivity and robust performance
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Integrated Vanquish UHPLC delivers superior chromatographic separation with excellent reproducibility
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Improved ion optics and collision cell design for maximum ion transmission and reduced noise
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Fast polarity switching for simultaneous quantitation of positive and negative ions
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Wide linear dynamic range enabling accurate quantitation from trace to high-concentration analytes
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Compact footprint and robust hardware optimized for high-throughput routine laboratories
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TraceFinder software with compliance-ready features for regulated workflows (21 CFR Part 11)
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Applications:
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Pharmaceuticals: Bioequivalence studies, drug metabolism, impurity profiling
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Food Safety: Monitoring pesticide residues, veterinary drugs, contaminants
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Environmental Analysis: Detection of pollutants, POPs, endocrine disruptors
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Clinical Research: Quantitative biomarker studies, therapeutic drug monitoring
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Forensic Toxicology: Detection and quantitation of drugs of abuse and toxicants
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Specifications:
| Specification | Detail |
|---|---|
| LC/MS Platform | TSQ Fortis Plus Triple Quadrupole LC-MS/MS with Vanquish UHPLC |
| MS System Type | Triple Quadrupole |
| Mass Range | m/z 10–2,000 |
| Ionization Modes | ESI (Electrospray Ionization), HESI (Heated Electrospray Ionization), APCI optional |
| Autosampler | Thermo Scientific Vanquish UHPLC Autosampler |
| Acquisition Modes | Full Scan, SIM, MRM (Multiple Reaction Monitoring), Quantitative MS/MS |
| Dynamic Range | >6 orders of magnitude |
| Mass Accuracy | Unit mass resolution in Q1 and Q3 quadrupoles |
| Scan Speed | >500 MRM transitions/sec |
| Vacuum System | Dual turbomolecular pumps with forepump |
| Interface | HESI-II heated electrospray source, optional APCI |
| Software | Thermo Scientific TraceFinder, Xcalibur, and Chromeleon software |
| Compliance | 21 CFR Part 11 compatible |