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Thermo Scientific TSQ Vantage Triple Quadrupole LC-MS/MS with UltiMate 3000 UHPLC ultra-sensitive quantitative LC-MS/MS system for pharmaceutical, clinical, food safety, and environmental analysis
  • Key Features:

    • High-sensitivity Triple Quadrupole LC-MS/MS system engineered for demanding quantitative workflows

    • Coupled with UltiMate 3000 UHPLC for precise, reproducible, and high-throughput chromatographic separations

    • S-Lens ion optics maximize ion transmission efficiency and improve overall sensitivity

    • Fast polarity switching (<5 ms) enables simultaneous quantitation of diverse analytes in a single run

    • Robust performance and durability, designed for long-term, high-sample-load environments

    • Wide dynamic range (>5–6 orders of magnitude) for accurate trace detection and bulk quantification

    • TraceFinder and Xcalibur software provide intuitive data acquisition, quantitation, and compliance features

  • Applications:

    • Pharmaceuticals: Bioequivalence studies, drug metabolism, impurity analysis

    • Food Safety: Monitoring of pesticide residues, veterinary drug residues, and mycotoxins

    • Environmental Testing: Analysis of pollutants, endocrine disruptors, and organic contaminants

    • Clinical Research: Quantitative biomarker assays, therapeutic drug monitoring

    • Forensics/Toxicology: Sensitive screening and quantitation of drugs and toxic substances

  • Specifications:

Specification Detail
LC/MS Platform TSQ Vantage Triple Quadrupole LC-MS/MS with UltiMate 3000 UHPLC
MS System Type Triple Quadrupole
Mass Range m/z 10–2,000
Ionization Modes ESI (Electrospray Ionization), HESI (Heated Electrospray Ionization), APCI optional
Autosampler UltiMate 3000 UHPLC autosampler with precise injection and temperature control
Acquisition Modes Full Scan, SIM, MRM (Multiple Reaction Monitoring)
Dynamic Range >5–6 orders of magnitude
Mass Accuracy Unit mass resolution (Q1/Q3 quadrupoles)
Scan Speed Up to ~500+ MRM transitions/sec
Vacuum System Dual turbomolecular pumps with forepump
Interface HESI-II heated electrospray source, optional APCI
Software Thermo Scientific Xcalibur, TraceFinder, Chromeleon
Compliance 21 CFR Part 11 compatible

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