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Key Features:
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The Thermo Scientific Vanquish Flex UHPLC is a modular UHPLC platform engineered for maximum robustness, reproducibility, and analytical power.
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Configurable with binary or quaternary pumps, offering high-pressure operation up to 1000 bar for routine to advanced separations.
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Diode Array Detector (DAD):
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Full spectral acquisition from 190–800 nm with up to 200 Hz data rate.
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Multi-wavelength detection with peak purity, spectral fingerprinting, and compound identification.
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Excellent sensitivity with low baseline noise for trace-level detection.
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Autosampler: high capacity with ultra-low carryover, precise injection volumes (0.1–100 µL), and <0.25% RSD precision.
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Column oven with multi-zone heating for maximum temperature stability (5–120 °C).
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Designed for ease of use, reliability, and scalability, allowing easy upgrades with MS detectors (LC/MS, LC-MS/MS).
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Full compatibility with Thermo Scientific Chromeleon Chromatography Data System (CDS) for control, analysis, and reporting.
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Built-in compliance support for GLP/GMP labs with 21 CFR Part 11 features.
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Engineered to provide low system dispersion, ensuring high efficiency and superior peak resolution.
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Applications:
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Pharmaceutical & Biotech: Impurity profiling, drug assay, dissolution studies, stability testing, and bioanalysis.
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Food & Beverage: Detection of additives, vitamins, phenolic compounds, sugars, organic acids, and contaminants.
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Environmental Testing: Monitoring of pesticides, herbicides, industrial contaminants, and endocrine disruptors.
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Chemical & Polymer Industry: QC of fine chemicals, surfactants, polymers, monomers, and intermediates.
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Forensics & Clinical Research: Toxicology screening, drug monitoring, metabolite profiling, biomarker analysis.
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Proteomics & Metabolomics: Separation of peptides, proteins, and small metabolites with UHPLC resolution.
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Academic & R&D: Advanced research, method development, and spectral library creation.
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Specifications:
Parameter | Specification |
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System Type | Ultra-High Performance Liquid Chromatography (UHPLC) |
Pump Options | Binary or quaternary gradient, flow range 0.001–8 mL/min |
Max Pressure | Up to 1000 bar |
Autosampler | Injection volumes 0.1–100 µL, carryover <0.004%, precision <0.25% RSD |
Column Oven | 5–120 °C with multi-zone heating |
Diode Array Detector (DAD) | 190–800 nm wavelength range, up to 200 Hz acquisition, multi-wavelength capability |
System Dispersion | Ultra-low for high-efficiency UHPLC separations |
Software | Thermo Scientific Chromeleon CDS |
Compliance | GLP/GMP, 21 CFR Part 11 |