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Waters SYNAPT XS Q-TOF LC-MS/MS with ACQUITY UPLC advanced high-resolution quadrupole time-of-flight mass spectrometer with ion mobility separation for proteomics, metabolomics, pharmaceutical, and biopharmaceutical research
  • Waters SYNAPT XS Q-TOF LC-MS/MS with ACQUITY UPLC advanced high-resolution quadrupole time-of-flight mass spectrometer with ion mobility separation for proteomics, metabolomics, pharmaceutical, and biopharmaceutical research
  • Waters SYNAPT XS Q-TOF LC-MS/MS with ACQUITY UPLC advanced high-resolution quadrupole time-of-flight mass spectrometer with ion mobility separation for proteomics, metabolomics, pharmaceutical, and biopharmaceutical research
Waters SYNAPT XS Q-TOF with ACQUITY UPLC High-Resolution LC-MS System
$0.00

  • Key Features:

    • Next-generation Q-TOF platform delivering improved resolution, sensitivity, and flexibility over the SYNAPT G2-Si.

    • Seamless integration with ACQUITY UPLC for high-speed, high-efficiency chromatographic separations.

    • Resolution exceeding 45,000 FWHM, enabling precise measurement of complex molecular species.

    • Tribrid architecture with quadrupole, ion mobility separation (IMS), and TOF detection for multidimensional characterization.

    • Enhanced ion mobility-enabled workflows for separating isomeric and conformational variants.

    • Data-independent acquisition (MSE, HDMSE) for simultaneous qualitative and quantitative analysis.

    • Compatible with UNIFI scientific information system for regulatory-ready workflows and streamlined data interpretation.

  • Applications:

    • Proteomics: Deep proteome profiling, PTM identification, quantitative proteomics.

    • Metabolomics/Lipidomics: Untargeted and targeted workflows, biomarker discovery.

    • Biopharmaceuticals: Intact mass analysis, peptide mapping, glycosylation profiling, higher-order structure characterization.

    • Pharmaceutical R&D: Drug metabolism, impurity profiling, degradation pathway elucidation.

    • Clinical & Translational Research: Biomarker validation, personalized medicine applications.

  • Specifications:

Specification Detail
LC/MS Platform SYNAPT XS Q-TOF LC-MS/MS with ACQUITY UPLC
MS System Type Quadrupole – Time-of-Flight (Q-TOF) Hybrid
Mass Range m/z 20–100,000
Resolution >45,000 FWHM
Ionization Modes ESI, NanoESI, APCI, APPI optional
Autosampler ACQUITY UPLC autosampler
Acquisition Modes MS, MS/MS, MSE, HDMSE (ion mobility-enabled)
Dynamic Range >5 orders of magnitude
Mass Accuracy <1 ppm with lock-mass calibration
Vacuum System Multi-stage turbomolecular pumping
Interface Z-Spray, NanoLockSpray ion source
Software UNIFI, MassLynx, Progenesis QI
Compliance 21 CFR Part 11 compatible

 

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